IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Alpine Global Management, LLC's Holding History (CIK: 0001581655)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 53,600 Value ($000) $4,240 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 55,900 Value ($000) $3,657 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 25,437 Value ($000) $1,005 Avg Close $32.73 Range $23.95 - $40.61

Q1 2025

Shares 28,097 Value ($000) $848 Avg Close $32.75 Range $29.61 - $35.48

Q4 2019

Shares 7,474 Value ($000) $452 Avg Close $59.58 Range $53.34 - $66.22

Q4 2015

Shares 20,609 Value ($000) $1,276 Avg Close $53.96 Range $38.30 - $65.34

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	53,600	$4,240	$75.30	$64.93 - $83.61
Q3 2025	55,900	$3,657	$48.82	$39.72 - $65.55
Q2 2025	25,437	$1,005	$32.73	$23.95 - $40.61
Q1 2025	28,097	$848	$32.75	$29.61 - $35.48
Q4 2019	7,474	$452	$59.58	$53.34 - $66.22
Q4 2015	20,609	$1,276	$53.96	$38.30 - $65.34