IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

MUFG Securities EMEA plc's Holding History (CIK: 0001597694)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 200,000 Value ($000) $6,086 Avg Close $31.48 Range $25.04 - $35.80

Q3 2020

Shares 12,374 Value ($000) $587 Avg Close $55.55 Range $47.19 - $63.49

Q2 2019

Shares 47,111 Value ($000) $3,028 Avg Close $70.69 Range $61.91 - $86.58

Q1 2019

Shares 47,111 Value ($000) $3,824 Avg Close $64.51 Range $52.45 - $81.59

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	200,000	$6,086	$31.48	$25.04 - $35.80
Q3 2020	12,374	$587	$55.55	$47.19 - $63.49
Q2 2019	47,111	$3,028	$70.69	$61.91 - $86.58
Q1 2019	47,111	$3,824	$64.51	$52.45 - $81.59