IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

BlueCrest Capital Management Ltd's Holding History (CIK: 0001610880)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 23,370 Value ($000) $1,529 Avg Close $48.82 Range $39.72 - $65.55

Q1 2025

Shares 24,800 Value ($000) $748 Avg Close $32.75 Range $29.61 - $35.48

Q4 2024

Shares 26,200 Value ($000) $916 Avg Close $37.38 Range $33.33 - $40.58

Q1 2019

Shares 34,935 Value ($000) $2,836 Avg Close $64.51 Range $52.45 - $81.59

Q4 2018

Shares 19,843 Value ($000) $1,073 Avg Close $51.00 Range $43.27 - $59.81

Q3 2018

Shares 10,500 Value ($000) $542 Avg Close $46.98 Range $41.05 - $54.85

Q2 2017

Shares 27,706 Value ($000) $1,409 Avg Close $46.57 Range $37.26 - $55.73

Q1 2017

Shares 11,491 Value ($000) $462 Avg Close $44.91 Range $37.29 - $56.91

Q4 2016

Shares 4,597 Value ($000) $220 Avg Close $39.57 Range $24.58 - $57.00

Q3 2016

Shares 13,808 Value ($000) $506 Avg Close $31.29 Range $23.26 - $40.82

Q4 2015

Shares 14,633 Value ($000) $906 Avg Close $53.96 Range $38.30 - $65.34

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	23,370	$1,529	$48.82	$39.72 - $65.55
Q1 2025	24,800	$748	$32.75	$29.61 - $35.48
Q4 2024	26,200	$916	$37.38	$33.33 - $40.58
Q1 2019	34,935	$2,836	$64.51	$52.45 - $81.59
Q4 2018	19,843	$1,073	$51.00	$43.27 - $59.81
Q3 2018	10,500	$542	$46.98	$41.05 - $54.85
Q2 2017	27,706	$1,409	$46.57	$37.26 - $55.73
Q1 2017	11,491	$462	$44.91	$37.29 - $56.91
Q4 2016	4,597	$220	$39.57	$24.58 - $57.00
Q3 2016	13,808	$506	$31.29	$23.26 - $40.82
Q4 2015	14,633	$906	$53.96	$38.30 - $65.34