IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

IQ EQ FUND MANAGEMENT (IRELAND) Ltd's Holding History (CIK: 0001620943)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 15,168 Value ($000) $1,200 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 15,284 Value ($000) $1,000 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 13,263 Value ($000) $524 Avg Close $32.73 Range $23.95 - $40.61

Q1 2025

Shares 8,059 Value ($000) $243 Avg Close $32.75 Range $29.61 - $35.48

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	15,168	$1,200	$75.30	$64.93 - $83.61
Q3 2025	15,284	$1,000	$48.82	$39.72 - $65.55
Q2 2025	13,263	$524	$32.73	$23.95 - $40.61
Q1 2025	8,059	$243	$32.75	$29.61 - $35.48