IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Cetera Investment Advisers's Holding History (CIK: 0001666741)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 10,856 Value ($000) $859 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 6,873 Value ($000) $450 Avg Close $48.82 Range $39.72 - $65.55

Q1 2024

Shares 21,758 Value ($000) $943 Avg Close $47.67 Range $41.60 - $54.44

Q4 2020

Shares 6,377 Value ($000) $361 Avg Close $49.83 Range $45.09 - $60.95

Q3 2020

Shares 4,225 Value ($000) $200 Avg Close $55.55 Range $47.19 - $63.49

Q2 2020

Shares 4,445 Value ($000) $262 Avg Close $55.63 Range $45.12 - $61.24

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	10,856	$859	$75.30	$64.93 - $83.61
Q3 2025	6,873	$450	$48.82	$39.72 - $65.55
Q1 2024	21,758	$943	$47.67	$41.60 - $54.44
Q4 2020	6,377	$361	$49.83	$45.09 - $60.95
Q3 2020	4,225	$200	$55.55	$47.19 - $63.49
Q2 2020	4,445	$262	$55.63	$45.12 - $61.24