IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Mn Services Vermogensbeheer B.V.'s Holding History (CIK: 0001666940)

Note: Option positions (PUT/CALL) are excluded.

Q2 2019

Shares 22,500 Value ($000) $1,446 Avg Close $70.69 Range $61.91 - $86.58

Q2 2016

Shares 2,973 Value ($000) $62 Avg Close $32.26 Range $19.59 - $46.75

Q1 2016

Shares 2,973 Value ($000) $106 Avg Close $40.62 Range $30.93 - $62.68

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2019	22,500	$1,446	$70.69	$61.91 - $86.58
Q2 2016	2,973	$62	$32.26	$19.59 - $46.75
Q1 2016	2,973	$106	$40.62	$30.93 - $62.68