IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

TRUE Private Wealth Advisors's Holding History (CIK: 0001667074)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019

Shares 2,475 Value ($000) $149 Avg Close $59.58 Range $53.34 - $66.22

Q2 2019

Shares 2,475 Value ($000) $159 Avg Close $70.69 Range $61.91 - $86.58

Q1 2019

Shares 2,540 Value ($000) $206 Avg Close $64.51 Range $52.45 - $81.59

Q3 2018

Shares 2,573 Value ($000) $132,715 Avg Close $46.98 Range $41.05 - $54.85

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2019	2,475	$149	$59.58	$53.34 - $66.22
Q2 2019	2,475	$159	$70.69	$61.91 - $86.58
Q1 2019	2,540	$206	$64.51	$52.45 - $81.59
Q3 2018	2,573	$132,715	$46.98	$41.05 - $54.85