IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Jacobi Capital Management LLC's Holding History (CIK: 0001689646)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020

Shares 427 Value ($000) $24 Avg Close $49.83 Range $45.09 - $60.95

Q3 2020

Shares 427 Value ($000) $20 Avg Close $55.55 Range $47.19 - $63.49

Q2 2020

Shares 427 Value ($000) $25 Avg Close $55.63 Range $45.12 - $61.24

Q1 2020

Shares 427 Value ($000) $20 Avg Close $55.74 Range $39.32 - $64.34

Q3 2016

Shares 37 Value ($000) $1 Avg Close $31.29 Range $23.26 - $40.82

Q2 2016

Shares 37 Value ($000) $1 Avg Close $32.26 Range $19.59 - $46.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2020	427	$24	$49.83	$45.09 - $60.95
Q3 2020	427	$20	$55.55	$47.19 - $63.49
Q2 2020	427	$25	$55.63	$45.12 - $61.24
Q1 2020	427	$20	$55.74	$39.32 - $64.34
Q3 2016	37	$1	$31.29	$23.26 - $40.82
Q2 2016	37	$1	$32.26	$19.59 - $46.75