IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Blueshift Asset Management, LLC's Holding History (CIK: 0001727827)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 10,443 Value ($000) $826 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 11,460 Value ($000) $750 Avg Close $48.82 Range $39.72 - $65.55

Q2 2019

Shares 3,423 Value ($000) $220 Avg Close $70.69 Range $61.91 - $86.58

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	10,443	$826	$75.30	$64.93 - $83.61
Q3 2025	11,460	$750	$48.82	$39.72 - $65.55
Q2 2019	3,423	$220	$70.69	$61.91 - $86.58