IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

SeaCrest Wealth Management, LLC's Holding History (CIK: 0001728121)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 653 Value ($000) $53 Avg Close $64.51 Range $52.45 - $81.59

Q4 2018

Shares 653 Value ($000) $35 Avg Close $51.00 Range $43.27 - $59.81

Q3 2018

Shares 2,112 Value ($000) $109 Avg Close $46.98 Range $41.05 - $54.85

Q2 2018

Shares 2,066 Value ($000) $86 Avg Close $44.30 Range $39.07 - $51.00

Q1 2018

Shares 1,918 Value ($000) $85 Avg Close $50.80 Range $43.38 - $56.47

Q4 2017

Shares 1,670 Value ($000) $84 Avg Close $54.84 Range $50.02 - $65.51

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	653	$53	$64.51	$52.45 - $81.59
Q4 2018	653	$35	$51.00	$43.27 - $59.81
Q3 2018	2,112	$109	$46.98	$41.05 - $54.85
Q2 2018	2,066	$86	$44.30	$39.07 - $51.00
Q1 2018	1,918	$85	$50.80	$43.38 - $56.47
Q4 2017	1,670	$84	$54.84	$50.02 - $65.51