IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Gryphon Financial Partners LLC's Holding History (CIK: 0001729094)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018

Shares 905 Value ($000) $38 Avg Close $44.30 Range $39.07 - $51.00

Q1 2018

Shares 905 Value ($000) $40 Avg Close $50.80 Range $43.38 - $56.47

Q4 2017

Shares 1,024 Value ($000) $52 Avg Close $54.84 Range $50.02 - $65.51

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2018	905	$38	$44.30	$39.07 - $51.00
Q1 2018	905	$40	$50.80	$43.38 - $56.47
Q4 2017	1,024	$52	$54.84	$50.02 - $65.51