IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Vident Advisory, LLC's Holding History (CIK: 0001744347)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 10,235 Value ($000) $810 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 11,551 Value ($000) $756 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 12,000 Value ($000) $474 Avg Close $32.73 Range $23.95 - $40.61

Q1 2024

Shares 4,796 Value ($000) $208 Avg Close $47.67 Range $41.60 - $54.44

Q4 2023

Shares 4,930 Value ($000) $249 Avg Close $47.90 Range $41.84 - $52.27

Q3 2023

Shares 5,586 Value ($000) $253 Avg Close $41.26 Range $38.26 - $47.72

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	10,235	$810	$75.30	$64.93 - $83.61
Q3 2025	11,551	$756	$48.82	$39.72 - $65.55
Q2 2025	12,000	$474	$32.73	$23.95 - $40.61
Q1 2024	4,796	$208	$47.67	$41.60 - $54.44
Q4 2023	4,930	$249	$47.90	$41.84 - $52.27
Q3 2023	5,586	$253	$41.26	$38.26 - $47.72