IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Quantinno Capital Management LP's Holding History (CIK: 0001759654)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 47,378 Value ($000) $3,748 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 36,115 Value ($000) $2,363 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 17,542 Value ($000) $693 Avg Close $32.73 Range $23.95 - $40.61

Q1 2025

Shares 8,515 Value ($000) $257 Avg Close $32.75 Range $29.61 - $35.48

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	47,378	$3,748	$75.30	$64.93 - $83.61
Q3 2025	36,115	$2,363	$48.82	$39.72 - $65.55
Q2 2025	17,542	$693	$32.73	$23.95 - $40.61
Q1 2025	8,515	$257	$32.75	$29.61 - $35.48