IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

TWINBEECH CAPITAL LP's Holding History (CIK: 0001769646)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 15,938 Value ($000) $481 Avg Close $32.75 Range $29.61 - $35.48

Q3 2024

Shares 235,477 Value ($000) $9,433 Avg Close $46.53 Range $39.48 - $52.34

Q1 2024

Shares 46,364 Value ($000) $2,010 Avg Close $47.67 Range $41.60 - $54.44

Q4 2023

Shares 29,729 Value ($000) $1,504 Avg Close $47.90 Range $41.84 - $52.27

Q1 2023

Shares 136,967 Value ($000) $4,895 Avg Close $37.55 Range $32.69 - $41.73

Q1 2021

Shares 22,750 Value ($000) $1,023 Avg Close $55.77 Range $41.42 - $64.37

Q3 2020

Shares 4,872 Value ($000) $231 Avg Close $55.55 Range $47.19 - $63.49

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	15,938	$481	$32.75	$29.61 - $35.48
Q3 2024	235,477	$9,433	$46.53	$39.48 - $52.34
Q1 2024	46,364	$2,010	$47.67	$41.60 - $54.44
Q4 2023	29,729	$1,504	$47.90	$41.84 - $52.27
Q1 2023	136,967	$4,895	$37.55	$32.69 - $41.73
Q1 2021	22,750	$1,023	$55.77	$41.42 - $64.37
Q3 2020	4,872	$231	$55.55	$47.19 - $63.49