IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Sanctuary Advisors, LLC's Holding History (CIK: 0001777271)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,502 Value ($000) $356 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 3,637 Value ($000) $238 Avg Close $48.82 Range $39.72 - $65.55

Q3 2024

Shares 9,277 Value ($000) $316 Avg Close $46.53 Range $39.48 - $52.34

Q2 2024

Shares 16,441 Value ($000) $684 Avg Close $41.01 Range $35.95 - $47.86

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,502	$356	$75.30	$64.93 - $83.61
Q3 2025	3,637	$238	$48.82	$39.72 - $65.55
Q3 2024	9,277	$316	$46.53	$39.48 - $52.34
Q2 2024	16,441	$684	$41.01	$35.95 - $47.86