IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Cinctive Capital Management LP's Holding History (CIK: 0001787258)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 13,726 Value ($000) $1,086 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 173,819 Value ($000) $11,371 Avg Close $48.82 Range $39.72 - $65.55

Q4 2023

Shares 73,256 Value ($000) $3,706 Avg Close $47.90 Range $41.84 - $52.27

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	13,726	$1,086	$75.30	$64.93 - $83.61
Q3 2025	173,819	$11,371	$48.82	$39.72 - $65.55
Q4 2023	73,256	$3,706	$47.90	$41.84 - $52.27