IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

Avion Wealth's Holding History (CIK: 0001792704)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 6 Value ($000) $0 Avg Close $75.30 Range $64.93 - $83.61

Q1 2025

Shares 54 Value ($000) $0 Avg Close $32.75 Range $29.61 - $35.48

Q4 2024

Shares 54 Value ($000) $0 Avg Close $37.38 Range $33.33 - $40.58

Q4 2023

Shares 25 Value ($000) $0 Avg Close $47.90 Range $41.84 - $52.27

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	6	$0	$75.30	$64.93 - $83.61
Q1 2025	54	$0	$32.75	$29.61 - $35.48
Q4 2024	54	$0	$37.38	$33.33 - $40.58
Q4 2023	25	$0	$47.90	$41.84 - $52.27