IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

ADAR1 Capital Management, LLC's Holding History (CIK: 0001940272)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 147,130 Value ($000) $11,639 Avg Close $75.30 Range $64.93 - $83.61

Q3 2025

Shares 133,818 Value ($000) $8,754 Avg Close $48.82 Range $39.72 - $65.55

Q2 2025

Shares 148,461 Value ($000) $5,866 Avg Close $32.73 Range $23.95 - $40.61

Q3 2024

Shares 700 Value ($000) $28 Avg Close $46.53 Range $39.48 - $52.34

Q2 2024

Shares 1,500 Value ($000) $71 Avg Close $41.01 Range $35.95 - $47.86

Q1 2024

Shares 2,900 Value ($000) $126 Avg Close $47.67 Range $41.60 - $54.44

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	147,130	$11,639	$75.30	$64.93 - $83.61
Q3 2025	133,818	$8,754	$48.82	$39.72 - $65.55
Q2 2025	148,461	$5,866	$32.73	$23.95 - $40.61
Q3 2024	700	$28	$46.53	$39.48 - $52.34
Q2 2024	1,500	$71	$41.01	$35.95 - $47.86
Q1 2024	2,900	$126	$47.67	$41.60 - $54.44