IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

LRI Investments, LLC's Holding History (CIK: 0002023325)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 110 Value ($000) $9 Avg Close $75.30 Range $64.93 - $83.61

Q4 2024

Shares 136 Value ($000) $5 Avg Close $37.38 Range $33.33 - $40.58

Q3 2024

Shares 136 Value ($000) $5 Avg Close $46.53 Range $39.48 - $52.34

Q2 2024

Shares 187 Value ($000) $9 Avg Close $41.01 Range $35.95 - $47.86

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	110	$9	$75.30	$64.93 - $83.61
Q4 2024	136	$5	$37.38	$33.33 - $40.58
Q3 2024	136	$5	$46.53	$39.48 - $52.34
Q2 2024	187	$9	$41.01	$35.95 - $47.86