IONIS PHARMACEUTICALS INC

CUSIP: 462222AD2 Class: NOTE 4/0

ROYAL BANK OF CANADA's Holding History (CIK: 0001000275)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025
Shares 195,000 Value ($000) $267 Avg Close — Range —
Q3 2025
Shares 313,000 Value ($000) $385 Avg Close — Range —
Q2 2025
Shares 1,983,000 Value ($000) $1,991 Avg Close — Range —
Q1 2025
Shares 1,983,000 Value ($000) $1,944 Avg Close — Range —
Q4 2024
Shares 7,008,000 Value ($000) $6,749 Avg Close — Range —
Q3 2024
Shares 6,211,000 Value ($000) $6,194 Avg Close — Range —
Q2 2024
Shares 3,411,000 Value ($000) $3,513 Avg Close — Range —
Q1 2024
Shares 3,517,000 Value ($000) $3,462 Avg Close — Range —
Q4 2023
Shares 3,568,000 Value ($000) $3,753 Avg Close — Range —
Q3 2023
Shares 3,643,000 Value ($000) $3,557 Avg Close — Range —
Q2 2023
Shares 2,903,000 Value ($000) $2,738 Avg Close — Range —
Q1 2023
Shares 3,378,000 Value ($000) $3,066 Avg Close — Range —
Q4 2022
Shares 5,653,000 Value ($000) $5,219 Avg Close — Range —
Q3 2022
Shares 4,483,000 Value ($000) $4,430 Avg Close — Range —