IRONWOOD PHARMACEUTICALS INC

Ticker: IRWD CUSIP: 46333X108 Class: COM CL A

Redmile Group, LLC's Holding History (CIK: 0001425738)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016

Shares 408,462 Value ($000) $6,486 Avg Close $11.69 Range $10.20 - $13.54

Q2 2016

Shares 442,711 Value ($000) $5,788 Avg Close $9.77 Range $7.59 - $11.11

Q1 2016

Shares 4,320,192 Value ($000) $47,263 Avg Close $8.25 Range $6.16 - $9.66

Q4 2015

Shares 3,671,344 Value ($000) $42,551 Avg Close $9.66 Range $8.42 - $10.57

Q3 2015

Shares 190,789 Value ($000) $1,988 Avg Close $9.33 Range $8.18 - $10.35

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2016	408,462	$6,486	$11.69	$10.20 - $13.54
Q2 2016	442,711	$5,788	$9.77	$7.59 - $11.11
Q1 2016	4,320,192	$47,263	$8.25	$6.16 - $9.66
Q4 2015	3,671,344	$42,551	$9.66	$8.42 - $10.57
Q3 2015	190,789	$1,988	$9.33	$8.18 - $10.35