Redmile Group, LLC Diversified Active

CIK: 0001425738 · Show all filings

Period: Q4 2025 (← Previous)

Filing Date: Feb 17, 2026

Total Value ($000): $1,357,911 (100.0% shares, 0.0% debt)

Holdings (34)

New Positions (3)

DBVT DBV TECHNOLOGIES S A 0.8%

Value ($000) $10,540 Shares 549,840 Est. Cost $19.17 Unrealized —

XENE XENON PHARMACEUTICALS INC 0.4%

Value ($000) $6,001 Shares 133,882 Est. Cost $42.00 Unrealized 0.0%

ORIC ORIC PHARMACEUTICALS INC 0.3%

Value ($000) $3,666 Shares 448,110 Est. Cost $11.51 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
DBVT	DBV TECHNOLOGIES S A	549,840	$10,540	0.8%	$19.17	—	SPONSORED ADS	23306J309
XENE	XENON PHARMACEUTICALS INC	133,882	$6,001	0.4%	$42.00	0.0%	COM	98420N105
ORIC	ORIC PHARMACEUTICALS INC	448,110	$3,666	0.3%	$11.51	0.0%	COM	68622P109

Increased Positions (11)

NRIX NURIX THERAPEUTICS INC 11.3%

Value ($000) $153,541 (+351.7%) Shares 8,093,908 (+120.0%) Est. Cost $17.18 Unrealized -16.4%

SRRK SCHOLAR ROCK HLDG CORP 16.9%

Value ($000) $229,978 (+58.2%) Shares 5,220,846 (+33.7%) Est. Cost $18.57 Unrealized +102.0%

IMNM IMMUNOME INC 9.0%

Value ($000) $122,831 (+108.8%) Shares 5,718,385 (+13.8%) Est. Cost $11.49 Unrealized +52.8%

KRYS KRYSTAL BIOTECH INC 12.3%

Value ($000) $167,081 (+43.1%) Shares 677,705 (+2.5%) Est. Cost $62.38 Unrealized +237.4%

ANNX ANNEXON INC 3.7%

Value ($000) $50,454 (+162.6%) Shares 10,050,644 (+59.5%) Est. Cost $9.79 Unrealized -61.0%

NUVB NUVATION BIO INC 2.1%

Value ($000) $28,343 (+152.7%) Shares 3,163,256 (+4.4%) Est. Cost $10.97 Unrealized -43.5%

RAPT RAPT THERAPEUTICS INC 2.2%

Value ($000) $30,006 (+110.6%) Shares 885,927 (+60.3%) Est. Cost $16.44 Unrealized +88.9%

REPL REPLIMUNE GROUP INC 0.8%

Value ($000) $10,690 (+376.1%) Shares 1,099,756 (+105.2%) Est. Cost $12.40 Unrealized -31.5%

NGNE NEUROGENE INC 2.2%

Value ($000) $30,068 (+33.6%) Shares 1,459,599 (+12.4%) Est. Cost $22.00 Unrealized +13.1%

IVVD INVIVYD INC 0.5%

Value ($000) $6,622 (+163.4%) Shares 2,681,159 (+17.3%) Est. Cost $16.17 Unrealized -87.1%

PLRX PLIANT THERAPEUTICS INC 0.1%

Value ($000) $1,972 (-16.3%) Shares 1,616,228 (+1.5%) Est. Cost $22.50 Unrealized -93.3%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
NRIX	NURIX THERAPEUTICS INC	8,093,908 (+120.0%)	$153,541 (+351.7%)	11.3%	$17.18	-16.4%	COM	67080M103
SRRK	SCHOLAR ROCK HLDG CORP	5,220,846 (+33.7%)	$229,978 (+58.2%)	16.9%	$18.57	+102.0%	COM	80706P103
IMNM	IMMUNOME INC	5,718,385 (+13.8%)	$122,831 (+108.8%)	9.0%	$11.49	+52.8%	COM	45257U108
KRYS	KRYSTAL BIOTECH INC	677,705 (+2.5%)	$167,081 (+43.1%)	12.3%	$62.38	+237.4%	COM	501147102
ANNX	ANNEXON INC	10,050,644 (+59.5%)	$50,454 (+162.6%)	3.7%	$9.79	-61.0%	COM	03589W102
NUVB	NUVATION BIO INC	3,163,256 (+4.4%)	$28,343 (+152.7%)	2.1%	$10.97	-43.5%	COM CL A	67080N101
RAPT	RAPT THERAPEUTICS INC	885,927 (+60.3%)	$30,006 (+110.6%)	2.2%	$16.44	+88.9%	COM NEW	75382E208
REPL	REPLIMUNE GROUP INC	1,099,756 (+105.2%)	$10,690 (+376.1%)	0.8%	$12.40	-31.5%	COM	76029N106
NGNE	NEUROGENE INC	1,459,599 (+12.4%)	$30,068 (+33.6%)	2.2%	$22.00	+13.1%	COM	64135M105
IVVD	INVIVYD INC	2,681,159 (+17.3%)	$6,622 (+163.4%)	0.5%	$16.17	-87.1%	COM	00534A102
PLRX	PLIANT THERAPEUTICS INC	1,616,228 (+1.5%)	$1,972 (-16.3%)	0.1%	$22.50	-93.3%	COM	729139105

Exited Positions (9)

— AKERO THERAPEUTICS INC 2.6%

Value ($000) $35,506 Shares 747,818 Est. Cost $33.38 Unrealized —

— 89BIO INC 1.6%

Value ($000) $21,655 Shares 1,473,136 Est. Cost $11.28 Unrealized —

KROS KEROS THERAPEUTICS INC 0.6%

Value ($000) $8,741 Shares 552,506 Est. Cost $59.30 Unrealized -70.4%

FOLD AMICUS THERAPEUTICS INC 0.5%

Value ($000) $6,124 Shares 777,178 Est. Cost $10.35 Unrealized -5.1%

XERS XERIS BIOPHARMA HOLDINGS INC 0.3%

Value ($000) $3,672 Shares 451,099 Est. Cost $2.16 Unrealized +264.4%

VTYX VENTYX BIOSCIENCES INC 0.2%

Value ($000) $3,338 Shares 1,073,386 Est. Cost $2.09 Unrealized +257.9%

— LAVA THERAPEUTICS NV 0.2%

Value ($000) $3,236 Shares 2,074,372 Est. Cost $15.19 Unrealized —

PRME PRIME MEDICINE INC 0.0%

Value ($000) $483 Shares 87,118 Est. Cost $14.27 Unrealized -68.8%

BOLD BOUNDLESS BIO INC 0.0%

Value ($000) $302 Shares 245,458 Est. Cost $14.25 Unrealized -91.3%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	AKERO THERAPEUTICS INC	747,818	$35,506	2.6%	$33.38	—	—	00973Y108
—	89BIO INC	1,473,136	$21,655	1.6%	$11.28	—	—	282559103
KROS	KEROS THERAPEUTICS INC	552,506	$8,741	0.6%	$59.30	-70.4%	—	492327101
FOLD	AMICUS THERAPEUTICS INC	777,178	$6,124	0.5%	$10.35	-5.1%	—	03152W109
XERS	XERIS BIOPHARMA HOLDINGS INC	451,099	$3,672	0.3%	$2.16	+264.4%	—	98422E103
VTYX	VENTYX BIOSCIENCES INC	1,073,386	$3,338	0.2%	$2.09	+257.9%	—	92332V107
—	LAVA THERAPEUTICS NV	2,074,372	$3,236	0.2%	$15.19	—	—	N51517105
PRME	PRIME MEDICINE INC	87,118	$483	0.0%	$14.27	-68.8%	—	74168J101
BOLD	BOUNDLESS BIO INC	245,458	$302	0.0%	$14.25	-91.3%	—	10170A100

Decreased Positions (10)

ZYME ZYMEWORKS INC 1.0%

Value ($000) $12,945 (-79.5%) Shares 491,654 (-86.7%) Est. Cost $7.05 Unrealized +209.5%

LIVN LIVANOVA PLC 0.5%

Value ($000) $7,264 (-85.0%) Shares 118,054 (-87.3%) Est. Cost $70.40 Unrealized -18.8%

STOK STOKE THERAPEUTICS INC 9.4%

Value ($000) $128,041 (+30.5%) Shares 4,034,070 (-3.4%) Est. Cost $9.00 Unrealized +234.1%

COGT COGENT BIOSCIENCES INC 3.8%

Value ($000) $51,075 (+61.0%) Shares 1,437,918 (-34.9%) Est. Cost $9.95 Unrealized +182.5%

RGNX REGENXBIO INC 4.6%

Value ($000) $62,911 (+38.9%) Shares 4,368,804 (-6.9%) Est. Cost $22.74 Unrealized -45.2%

ESTA ESTABLISHMENT LABS HLDGS INC 0.6%

Value ($000) $8,211 (+54.8%) Shares 112,664 (-12.9%) Est. Cost $44.21 Unrealized +36.6%

ALXO ALX ONCOLOGY HLDGS INC 0.3%

Value ($000) $3,689 (-39.5%) Shares 3,264,718 (-2.0%) Est. Cost $15.46 Unrealized -90.2%

BEAM BEAM THERAPEUTICS INC 2.6%

Value ($000) $35,644 (+5.8%) Shares 1,285,859 (-7.3%) Est. Cost $26.47 Unrealized -3.6%

SLDB SOLID BIOSCIENCES INC 0.8%

Value ($000) $10,493 (-10.5%) Shares 1,860,542 (-2.0%) Est. Cost $4.65 Unrealized +16.5%

CLDX CELLDEX THERAPEUTICS INC NEW 0.6%

Value ($000) $7,695 (-9.0%) Shares 283,308 (-13.4%) Est. Cost $11.60 Unrealized +127.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ZYME	ZYMEWORKS INC	491,654 (-86.7%)	$12,945 (-79.5%)	1.0%	$7.05	+209.5%	COM	98985Y108
LIVN	LIVANOVA PLC	118,054 (-87.3%)	$7,264 (-85.0%)	0.5%	$70.40	-18.8%	SHS	G5509L101
STOK	STOKE THERAPEUTICS INC	4,034,070 (-3.4%)	$128,041 (+30.5%)	9.4%	$9.00	+234.1%	COM	86150R107
COGT	COGENT BIOSCIENCES INC	1,437,918 (-34.9%)	$51,075 (+61.0%)	3.8%	$9.95	+182.5%	COM	19240Q201
RGNX	REGENXBIO INC	4,368,804 (-6.9%)	$62,911 (+38.9%)	4.6%	$22.74	-45.2%	COM	75901B107
ESTA	ESTABLISHMENT LABS HLDGS INC	112,664 (-12.9%)	$8,211 (+54.8%)	0.6%	$44.21	+36.6%	COM	G31249108
ALXO	ALX ONCOLOGY HLDGS INC	3,264,718 (-2.0%)	$3,689 (-39.5%)	0.3%	$15.46	-90.2%	COM	00166B105
BEAM	BEAM THERAPEUTICS INC	1,285,859 (-7.3%)	$35,644 (+5.8%)	2.6%	$26.47	-3.6%	COM	07373V105
SLDB	SOLID BIOSCIENCES INC	1,860,542 (-2.0%)	$10,493 (-10.5%)	0.8%	$4.65	+16.5%	COM NEW	83422E204
CLDX	CELLDEX THERAPEUTICS INC NEW	283,308 (-13.4%)	$7,695 (-9.0%)	0.6%	$11.60	+127.1%	COM NEW	15117B202

Unchanged Positions (10)

ADCT ADC THERAPEUTICS SA 4.1%

Value ($000) $55,304 Shares 15,666,731 Est. Cost $19.52 Unrealized -79.2%

STTK SHATTUCK LABS INC 1.5%

Value ($000) $20,220 Shares 5,539,724 Est. Cost $32.14 Unrealized -92.6%

IDYA IDEAYA BIOSCIENCES INC 1.9%

Value ($000) $25,652 Shares 742,017 Est. Cost $27.49 Unrealized +16.0%

CBLL CERIBELL INC 0.7%

Value ($000) $9,545 Shares 435,239 Est. Cost $27.25 Unrealized -43.0%

ABSI ABSCI CORPORATION 2.1%

Value ($000) $28,804 Shares 8,253,316 Est. Cost $19.01 Unrealized -80.8%

FATE FATE THERAPEUTICS INC 0.9%

Value ($000) $12,649 Shares 12,872,946 Est. Cost $13.12 Unrealized -90.9%

SLN SILENCE THERAPEUTICS PLC 1.0%

Value ($000) $13,162 Shares 2,164,777 Est. Cost $18.53 Unrealized —

ATRA ATARA BIOTHERAPEUTICS INC 0.6%

Value ($000) $7,990 Shares 441,701 Est. Cost $15.04 Unrealized -0.7%

— REPARE THERAPEUTICS INC 0.3%

Value ($000) $4,124 Shares 1,586,174 Est. Cost $30.51 Unrealized —

KLRS KALARIS THERAPEUTICS INC 0.1%

Value ($000) $700 Shares 82,955 Est. Cost $9.79 Unrealized -34.7%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ADCT	ADC THERAPEUTICS SA	15,666,731	$55,304	4.1%	$19.52	-79.2%	SHS	H0036K147
STTK	SHATTUCK LABS INC	5,539,724	$20,220	1.5%	$32.14	-92.6%	COM	82024L103
IDYA	IDEAYA BIOSCIENCES INC	742,017	$25,652	1.9%	$27.49	+16.0%	COM	45166A102
CBLL	CERIBELL INC	435,239	$9,545	0.7%	$27.25	-43.0%	COM	15678C102
ABSI	ABSCI CORPORATION	8,253,316	$28,804	2.1%	$19.01	-80.8%	COM	00091E109
FATE	FATE THERAPEUTICS INC	12,872,946	$12,649	0.9%	$13.12	-90.9%	COM	31189P102
SLN	SILENCE THERAPEUTICS PLC	2,164,777	$13,162	1.0%	$18.53	—	ADS	82686Q101
ATRA	ATARA BIOTHERAPEUTICS INC	441,701	$7,990	0.6%	$15.04	-0.7%	COM NEW	046513206
—	REPARE THERAPEUTICS INC	1,586,174	$4,124	0.3%	$30.51	—	COM	760273102
KLRS	KALARIS THERAPEUTICS INC	82,955	$700	0.1%	$9.79	-34.7%	COM	482929106