ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

NORTHERN TRUST CORP's Holding History (CIK: 0000073124)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 627,075 Value ($000) $25,346 Avg Close — Range —
Q2 2015
Shares 1,398,254 Value ($000) $80,469 Avg Close — Range —
Q1 2015
Shares 1,571,219 Value ($000) $100,039 Avg Close — Range —
Q4 2014
Shares 1,346,893 Value ($000) $83,157 Avg Close — Range —
Q3 2014
Shares 1,379,382 Value ($000) $53,561 Avg Close — Range —
Q2 2014
Shares 1,357,312 Value ($000) $46,760 Avg Close — Range —
Q1 2014
Shares 1,522,627 Value ($000) $65,793 Avg Close — Range —
Q4 2013
Shares 1,665,136 Value ($000) $66,338 Avg Close — Range —
Q3 2013
Shares 1,621,618 Value ($000) $60,876 Avg Close — Range —
Q2 2013
Shares 1,638,621 Value ($000) $44,029 Avg Close — Range —