ISIS PHARMACEUTICALS INC

CUSIP: 464330109 Class: CMN

PNC Financial Services Group, Inc.'s Holding History (CIK: 0000713676)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 26,924 Value ($000) $1,087 Avg Close — Range —
Q2 2015
Shares 25,153 Value ($000) $1,449 Avg Close — Range —
Q1 2015
Shares 25,599 Value ($000) $1,629 Avg Close — Range —
Q4 2014
Shares 24,429 Value ($000) $1,509 Avg Close — Range —
Q3 2014
Shares 21,877 Value ($000) $849 Avg Close — Range —
Q2 2014
Shares 24,877 Value ($000) $857 Avg Close — Range —
Q1 2014
Shares 32,121 Value ($000) $1,388 Avg Close — Range —
Q4 2013
Shares 32,495 Value ($000) $1,295 Avg Close — Range —
Q3 2013
Shares 29,014 Value ($000) $1,090 Avg Close — Range —
Q2 2013
Shares 18,826 Value ($000) $505 Avg Close — Range —