JANUX THERAPEUTICS INC

Ticker: JANX CUSIP: 47103J105 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 471,009 Value ($000) $6,500 Avg Close $23.52 Range $13.62 - $35.34

Q3 2025

Shares 103,476 Value ($000) $2,529 Avg Close $24.35 Range $21.73 - $28.39

Q2 2025

Shares 104,382 Value ($000) $2,411 Avg Close $26.35 Range $22.48 - $33.97

Q4 2024

Shares 59,974 Value ($000) $3,211 Avg Close $52.89 Range $40.02 - $71.71

Q3 2024

Shares 77,192 Value ($000) $3,507 Avg Close $43.50 Range $34.51 - $52.23

Q2 2024

Shares 103,601 Value ($000) $4,340 Avg Close $46.95 Range $34.63 - $65.60

Q1 2024

Shares 224,720 Value ($000) $8,461 Avg Close $21.78 Range $7.79 - $58.69

Q4 2023

Shares 44,108 Value ($000) $473 Avg Close $8.65 Range $5.65 - $11.92

Q3 2023

Shares 19,241 Value ($000) $194 Avg Close $11.53 Range $9.26 - $14.92

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	471,009	$6,500	$23.52	$13.62 - $35.34
Q3 2025	103,476	$2,529	$24.35	$21.73 - $28.39
Q2 2025	104,382	$2,411	$26.35	$22.48 - $33.97
Q4 2024	59,974	$3,211	$52.89	$40.02 - $71.71
Q3 2024	77,192	$3,507	$43.50	$34.51 - $52.23
Q2 2024	103,601	$4,340	$46.95	$34.63 - $65.60
Q1 2024	224,720	$8,461	$21.78	$7.79 - $58.69
Q4 2023	44,108	$473	$8.65	$5.65 - $11.92
Q3 2023	19,241	$194	$11.53	$9.26 - $14.92