KALEIDO BIOSCIENCES INC

Ticker: KLDO CUSIP: 483347100 Class: COM

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022

Shares 86,887 Value ($000) $143 Avg Close $1.78 Range $1.30 - $2.73

Q4 2021

Shares 39,374 Value ($000) $94 Avg Close $4.07 Range $2.37 - $6.07

Q3 2021

Shares 29,800 Value ($000) $163 Avg Close $6.20 Range $5.10 - $8.25

Q1 2021

Shares 54,100 Value ($000) $438 Avg Close $10.89 Range $7.00 - $20.50

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2022	86,887	$143	$1.78	$1.30 - $2.73
Q4 2021	39,374	$94	$4.07	$2.37 - $6.07
Q3 2021	29,800	$163	$6.20	$5.10 - $8.25
Q1 2021	54,100	$438	$10.89	$7.00 - $20.50