KARYOPHARM THERAPEUTICS INC

Ticker: KPTI CUSIP: 48576U205 Class: 0

Ikarian Capital, LLC's Holding History (CIK: 0001778253)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 544,554 Value ($000) $4,008 Avg Close $6.12 Range $4.51 - $7.70

Q3 2025

Shares 27,257 Value ($000) $178 Avg Close $5.38 Range $3.65 - $8.15

Q2 2025

Shares 27,257 Value ($000) $117 Avg Close $4.91 Range $3.51 - $7.90

Q1 2025

Shares 27,257 Value ($000) $102 Avg Close $8.54 Range $3.73 - $12.45

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	544,554	$4,008	$6.12	$4.51 - $7.70
Q3 2025	27,257	$178	$5.38	$3.65 - $8.15
Q2 2025	27,257	$117	$4.91	$3.51 - $7.90
Q1 2025	27,257	$102	$8.54	$3.73 - $12.45