KARYOPHARM THERAPEUTICS INC

Ticker: KPTI CUSIP: 48576U205 Class: 0

XTX Topco Ltd's Holding History (CIK: 0001828301)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 11,904 Value ($000) $88 Avg Close $6.12 Range $4.51 - $7.70

Q3 2025

Shares 14,402 Value ($000) $94 Avg Close $5.38 Range $3.65 - $8.15

Q2 2025

Shares 13,056 Value ($000) $56 Avg Close $4.91 Range $3.51 - $7.90

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	11,904	$88	$6.12	$4.51 - $7.70
Q3 2025	14,402	$94	$5.38	$3.65 - $8.15
Q2 2025	13,056	$56	$4.91	$3.51 - $7.90