KARYOPHARM THERAPEUTICS INC

Ticker: KPTI CUSIP: 48576U205 Class: 0

T. Rowe Price Investment Management, Inc.'s Holding History (CIK: 0001897612)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 585,908 Value ($000) $4 Avg Close $6.12 Range $4.51 - $7.70

Q3 2025

Shares 700,992 Value ($000) $5 Avg Close $5.38 Range $3.65 - $8.15

Q2 2025

Shares 728,766 Value ($000) $3 Avg Close $4.91 Range $3.51 - $7.90

Q1 2025

Shares 139,646 Value ($000) $1 Avg Close $8.54 Range $3.73 - $12.45

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	585,908	$4	$6.12	$4.51 - $7.70
Q3 2025	700,992	$5	$5.38	$3.65 - $8.15
Q2 2025	728,766	$3	$4.91	$3.51 - $7.90
Q1 2025	139,646	$1	$8.54	$3.73 - $12.45