KERYX BIOPHARMACEUTICALS INC

CUSIP: 492515101 Class: COMMON STOCK

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016

Shares 311,600 Value ($000) $1,655 Avg Close — Range —

Q2 2016

Shares 562,900 Value ($000) $3,726 Avg Close — Range —

Q3 2015

Shares 700,000 Value ($000) $2,464 Avg Close — Range —

Q1 2015

Shares 230,000 Value ($000) $2,928 Avg Close — Range —

Q4 2014

Shares 200,000 Value ($000) $2,830 Avg Close — Range —

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2016	311,600	$1,655	—	—
Q2 2016	562,900	$3,726	—	—
Q3 2015	700,000	$2,464	—	—
Q1 2015	230,000	$2,928	—	—
Q4 2014	200,000	$2,830	—	—