KODIAK SCIENCES INC

Ticker: KOD CUSIP: 50015M109 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 51,671 Value ($000) $1,445 Avg Close $20.48 Range $10.94 - $31.18

Q3 2025

Shares 138,261 Value ($000) $2,263 Avg Close $8.62 Range $3.60 - $19.39

Q2 2025

Shares 53,397 Value ($000) $199 Avg Close $3.54 Range $1.92 - $5.14

Q1 2025

Shares 106,664 Value ($000) $299 Avg Close $5.44 Range $2.67 - $9.94

Q4 2024

Shares 49,406 Value ($000) $492 Avg Close $5.75 Range $2.50 - $11.60

Q3 2024

Shares 39,465 Value ($000) $103 Avg Close $2.66 Range $2.19 - $3.33

Q2 2024

Shares 124,411 Value ($000) $292 Avg Close $3.39 Range $2.25 - $5.39

Q1 2024

Shares 69,357 Value ($000) $365 Avg Close $4.90 Range $2.87 - $7.77

Q4 2023

Shares 333,099 Value ($000) $1,013 Avg Close $2.22 Range $1.37 - $3.43

Q3 2023

Shares 134,295 Value ($000) $242 Avg Close $3.53 Range $1.78 - $7.84

Q2 2023

Shares 86,674 Value ($000) $598 Avg Close $6.12 Range $4.25 - $9.80

Q1 2023

Shares 99,216 Value ($000) $615 Avg Close $7.00 Range $4.62 - $9.01

Q4 2022

Shares 175,967 Value ($000) $1,260 Avg Close $7.18 Range $6.32 - $8.37

Q3 2022

Shares 387,660 Value ($000) $3,000 Avg Close $9.72 Range $7.31 - $12.80

Q2 2022

Shares 237,124 Value ($000) $1,812 Avg Close $7.02 Range $4.90 - $9.62

Q1 2022

Shares 989,575 Value ($000) $7,640 Avg Close $39.02 Range $6.81 - $90.24

Q3 2021

Shares 138,849 Value ($000) $13,327 Avg Close $92.41 Range $80.00 - $107.30

Q2 2021

Shares 247,987 Value ($000) $23,063 Avg Close $95.97 Range $73.19 - $128.33

Q1 2021

Shares 65,699 Value ($000) $7,450 Avg Close $136.58 Range $108.10 - $171.21

Q4 2020

Shares 5,400 Value ($000) $793 Avg Close $111.49 Range $59.36 - $159.18

Q3 2020

Shares 22,963 Value ($000) $1,360 Avg Close $50.19 Range $42.97 - $60.68

Q2 2020

Shares 84,567 Value ($000) $4,577 Avg Close $56.40 Range $41.08 - $68.50

Q1 2020

Shares 92,792 Value ($000) $4,426 Avg Close $59.99 Range $35.49 - $82.75

Q4 2019

Shares 27,567 Value ($000) $1,983 Avg Close $36.38 Range $13.39 - $81.00

Q3 2019

Shares 14,817 Value ($000) $213 Avg Close $13.06 Range $9.47 - $18.07

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	51,671	$1,445	$20.48	$10.94 - $31.18
Q3 2025	138,261	$2,263	$8.62	$3.60 - $19.39
Q2 2025	53,397	$199	$3.54	$1.92 - $5.14
Q1 2025	106,664	$299	$5.44	$2.67 - $9.94
Q4 2024	49,406	$492	$5.75	$2.50 - $11.60
Q3 2024	39,465	$103	$2.66	$2.19 - $3.33
Q2 2024	124,411	$292	$3.39	$2.25 - $5.39
Q1 2024	69,357	$365	$4.90	$2.87 - $7.77
Q4 2023	333,099	$1,013	$2.22	$1.37 - $3.43
Q3 2023	134,295	$242	$3.53	$1.78 - $7.84
Q2 2023	86,674	$598	$6.12	$4.25 - $9.80
Q1 2023	99,216	$615	$7.00	$4.62 - $9.01
Q4 2022	175,967	$1,260	$7.18	$6.32 - $8.37
Q3 2022	387,660	$3,000	$9.72	$7.31 - $12.80
Q2 2022	237,124	$1,812	$7.02	$4.90 - $9.62
Q1 2022	989,575	$7,640	$39.02	$6.81 - $90.24
Q3 2021	138,849	$13,327	$92.41	$80.00 - $107.30
Q2 2021	247,987	$23,063	$95.97	$73.19 - $128.33
Q1 2021	65,699	$7,450	$136.58	$108.10 - $171.21
Q4 2020	5,400	$793	$111.49	$59.36 - $159.18
Q3 2020	22,963	$1,360	$50.19	$42.97 - $60.68
Q2 2020	84,567	$4,577	$56.40	$41.08 - $68.50
Q1 2020	92,792	$4,426	$59.99	$35.49 - $82.75
Q4 2019	27,567	$1,983	$36.38	$13.39 - $81.00
Q3 2019	14,817	$213	$13.06	$9.47 - $18.07