KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

BARCLAYS PLC's Holding History (CIK: 0000312069)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 60,062 Value ($000) $14,808 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 56,540 Value ($000) $10,292 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 92,871 Value ($000) $12,766 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 44,997 Value ($000) $8,113 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 52,429 Value ($000) $8,214 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 56,540 Value ($000) $10 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 19,088 Value ($000) $3,505 Avg Close $167.89 Range $144.00 - $191.78

Q1 2024

Shares 21,614 Value ($000) $3,846 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 64,179 Value ($000) $7,962 Avg Close $110.89 Range $93.95 - $129.85

Q3 2023

Shares 39,520 Value ($000) $4,584 Avg Close $122.00 Range $106.92 - $132.68

Q2 2023

Shares 46,627 Value ($000) $5 Avg Close $102.10 Range $77.09 - $131.80

Q1 2023

Shares 29,893 Value ($000) $2 Avg Close $78.56 Range $69.81 - $89.59

Q4 2022

Shares 36,348 Value ($000) $3 Avg Close $74.22 Range $61.11 - $81.97

Q3 2022

Shares 33,131 Value ($000) $2,309 Avg Close $72.25 Range $63.02 - $85.11

Q2 2022

Shares 1,206 Value ($000) $79 Avg Close $62.21 Range $47.67 - $74.53

Q1 2022

Shares 3,395 Value ($000) $225 Avg Close $62.42 Range $50.03 - $73.94

Q4 2021

Shares 25,861 Value ($000) $1,808 Avg Close $58.21 Range $38.86 - $102.99

Q3 2021

Shares 12,700 Value ($000) $663 Avg Close $59.20 Range $51.04 - $72.55

Q2 2021

Shares 3,366 Value ($000) $228 Avg Close $69.80 Range $59.29 - $83.00

Q1 2021

Shares 22,021 Value ($000) $1,697 Avg Close $72.70 Range $57.06 - $87.29

Q4 2020

Shares 24,935 Value ($000) $1,496 Avg Close $49.94 Range $40.04 - $62.95

Q3 2020

Shares 26,694 Value ($000) $1,150 Avg Close $43.43 Range $37.68 - $48.80

Q2 2020

Shares 6,804 Value ($000) $282 Avg Close $48.11 Range $35.33 - $61.86

Q1 2020

Shares 9,320 Value ($000) $402 Avg Close $52.30 Range $33.09 - $66.85

Q4 2019

Shares 10,807 Value ($000) $598 Avg Close $49.06 Range $31.89 - $66.50

Q3 2019

Shares 10,478 Value ($000) $364 Avg Close $44.70 Range $33.62 - $51.67

Q2 2019

Shares 10,938 Value ($000) $440 Avg Close $32.69 Range $22.02 - $46.90

Q1 2019

Shares 35,986 Value ($000) $1,184 Avg Close $23.57 Range $18.50 - $33.12

Q4 2018

Shares 37,389 Value ($000) $777 Avg Close $20.94 Range $14.30 - $28.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	60,062	$14,808	$210.47	$175.85 - $265.92
Q3 2025	56,540	$10,292	$149.68	$130.50 - $178.20
Q2 2025	92,871	$12,766	$146.88	$122.80 - $182.16
Q1 2025	44,997	$8,113	$168.21	$141.72 - $197.94
Q4 2024	52,429	$8,214	$177.39	$154.16 - $207.84
Q3 2024	56,540	$10	$192.81	$164.81 - $219.34
Q2 2024	19,088	$3,505	$167.89	$144.00 - $191.78
Q1 2024	21,614	$3,846	$138.91	$107.50 - $189.97
Q4 2023	64,179	$7,962	$110.89	$93.95 - $129.85
Q3 2023	39,520	$4,584	$122.00	$106.92 - $132.68
Q2 2023	46,627	$5	$102.10	$77.09 - $131.80
Q1 2023	29,893	$2	$78.56	$69.81 - $89.59
Q4 2022	36,348	$3	$74.22	$61.11 - $81.97
Q3 2022	33,131	$2,309	$72.25	$63.02 - $85.11
Q2 2022	1,206	$79	$62.21	$47.67 - $74.53
Q1 2022	3,395	$225	$62.42	$50.03 - $73.94
Q4 2021	25,861	$1,808	$58.21	$38.86 - $102.99
Q3 2021	12,700	$663	$59.20	$51.04 - $72.55
Q2 2021	3,366	$228	$69.80	$59.29 - $83.00
Q1 2021	22,021	$1,697	$72.70	$57.06 - $87.29
Q4 2020	24,935	$1,496	$49.94	$40.04 - $62.95
Q3 2020	26,694	$1,150	$43.43	$37.68 - $48.80
Q2 2020	6,804	$282	$48.11	$35.33 - $61.86
Q1 2020	9,320	$402	$52.30	$33.09 - $66.85
Q4 2019	10,807	$598	$49.06	$31.89 - $66.50
Q3 2019	10,478	$364	$44.70	$33.62 - $51.67
Q2 2019	10,938	$440	$32.69	$22.02 - $46.90
Q1 2019	35,986	$1,184	$23.57	$18.50 - $33.12
Q4 2018	37,389	$777	$20.94	$14.30 - $28.75