KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

SEI INVESTMENTS CO's Holding History (CIK: 0000350894)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 32,310 Value ($000) $7,966 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 23,393 Value ($000) $4,130 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 19,300 Value ($000) $2,653 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 18,691 Value ($000) $3,370 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 21,164 Value ($000) $3,316 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 34,249 Value ($000) $6,234 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 40,115 Value ($000) $7,367 Avg Close $167.89 Range $144.00 - $191.78

Q1 2024

Shares 33,752 Value ($000) $6,005 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 14,784 Value ($000) $1,834 Avg Close $110.89 Range $93.95 - $129.85

Q3 2023

Shares 34,901 Value ($000) $4,049 Avg Close $122.00 Range $106.92 - $132.68

Q2 2023

Shares 13,231 Value ($000) $1,553 Avg Close $102.10 Range $77.09 - $131.80

Q1 2023

Shares 12,952 Value ($000) $1,037 Avg Close $78.56 Range $69.81 - $89.59

Q4 2022

Shares 16,510 Value ($000) $1,308 Avg Close $74.22 Range $61.11 - $81.97

Q3 2022

Shares 16,890 Value ($000) $1,177 Avg Close $72.25 Range $63.02 - $85.11

Q2 2022

Shares 17,090 Value ($000) $1,122 Avg Close $62.21 Range $47.67 - $74.53

Q1 2022

Shares 19,413 Value ($000) $1,292 Avg Close $62.42 Range $50.03 - $73.94

Q4 2021

Shares 16,415 Value ($000) $1,148 Avg Close $58.21 Range $38.86 - $102.99

Q3 2021

Shares 6,978 Value ($000) $364 Avg Close $59.20 Range $51.04 - $72.55

Q2 2021

Shares 7,111 Value ($000) $484 Avg Close $69.80 Range $59.29 - $83.00

Q1 2021

Shares 7,250 Value ($000) $559 Avg Close $72.70 Range $57.06 - $87.29

Q4 2020

Shares 7,506 Value ($000) $450 Avg Close $49.94 Range $40.04 - $62.95

Q3 2020

Shares 7,506 Value ($000) $323 Avg Close $43.43 Range $37.68 - $48.80

Q2 2020

Shares 7,506 Value ($000) $311 Avg Close $48.11 Range $35.33 - $61.86

Q1 2020

Shares 9,590 Value ($000) $415 Avg Close $52.30 Range $33.09 - $66.85

Q4 2019

Shares 8,652 Value ($000) $479 Avg Close $49.06 Range $31.89 - $66.50

Q3 2019

Shares 10,800 Value ($000) $375 Avg Close $44.70 Range $33.62 - $51.67

Q2 2019

Shares 12,101 Value ($000) $487 Avg Close $32.69 Range $22.02 - $46.90

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	32,310	$7,966	$210.47	$175.85 - $265.92
Q3 2025	23,393	$4,130	$149.68	$130.50 - $178.20
Q2 2025	19,300	$2,653	$146.88	$122.80 - $182.16
Q1 2025	18,691	$3,370	$168.21	$141.72 - $197.94
Q4 2024	21,164	$3,316	$177.39	$154.16 - $207.84
Q3 2024	34,249	$6,234	$192.81	$164.81 - $219.34
Q2 2024	40,115	$7,367	$167.89	$144.00 - $191.78
Q1 2024	33,752	$6,005	$138.91	$107.50 - $189.97
Q4 2023	14,784	$1,834	$110.89	$93.95 - $129.85
Q3 2023	34,901	$4,049	$122.00	$106.92 - $132.68
Q2 2023	13,231	$1,553	$102.10	$77.09 - $131.80
Q1 2023	12,952	$1,037	$78.56	$69.81 - $89.59
Q4 2022	16,510	$1,308	$74.22	$61.11 - $81.97
Q3 2022	16,890	$1,177	$72.25	$63.02 - $85.11
Q2 2022	17,090	$1,122	$62.21	$47.67 - $74.53
Q1 2022	19,413	$1,292	$62.42	$50.03 - $73.94
Q4 2021	16,415	$1,148	$58.21	$38.86 - $102.99
Q3 2021	6,978	$364	$59.20	$51.04 - $72.55
Q2 2021	7,111	$484	$69.80	$59.29 - $83.00
Q1 2021	7,250	$559	$72.70	$57.06 - $87.29
Q4 2020	7,506	$450	$49.94	$40.04 - $62.95
Q3 2020	7,506	$323	$43.43	$37.68 - $48.80
Q2 2020	7,506	$311	$48.11	$35.33 - $61.86
Q1 2020	9,590	$415	$52.30	$33.09 - $66.85
Q4 2019	8,652	$479	$49.06	$31.89 - $66.50
Q3 2019	10,800	$375	$44.70	$33.62 - $51.67
Q2 2019	12,101	$487	$32.69	$22.02 - $46.90