KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

DIMENSIONAL FUND ADVISORS LP's Holding History (CIK: 0000354204)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 492,968 Value ($000) $121,538 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 533,964 Value ($000) $94,261 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 505,889 Value ($000) $69,542 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 533,919 Value ($000) $96,270 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 588,599 Value ($000) $92,214 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 600,261 Value ($000) $109,260 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 580,452 Value ($000) $106,593 Avg Close $167.89 Range $144.00 - $191.78

Q1 2024

Shares 572,915 Value ($000) $101,939 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 550,806 Value ($000) $68,337 Avg Close $110.89 Range $93.95 - $129.85

Q3 2023

Shares 520,637 Value ($000) $60,396 Avg Close $122.00 Range $106.92 - $132.68

Q2 2023

Shares 486,597 Value ($000) $57,125 Avg Close $102.10 Range $77.09 - $131.80

Q1 2023

Shares 462,090 Value ($000) $36,994 Avg Close $78.56 Range $69.81 - $89.59

Q4 2022

Shares 389,285 Value ($000) $31 Avg Close $74.22 Range $61.11 - $81.97

Q3 2022

Shares 358,837 Value ($000) $25,012 Avg Close $72.25 Range $63.02 - $85.11

Q2 2022

Shares 275,923 Value ($000) $18,116 Avg Close $62.21 Range $47.67 - $74.53

Q1 2022

Shares 262,463 Value ($000) $17,465 Avg Close $62.42 Range $50.03 - $73.94

Q4 2021

Shares 150,641 Value ($000) $10,538 Avg Close $58.21 Range $38.86 - $102.99

Q3 2021

Shares 163,864 Value ($000) $8,557 Avg Close $59.20 Range $51.04 - $72.55

Q2 2021

Shares 213,712 Value ($000) $14,533 Avg Close $69.80 Range $59.29 - $83.00

Q1 2021

Shares 145,332 Value ($000) $11,192 Avg Close $72.70 Range $57.06 - $87.29

Q4 2020

Shares 68,344 Value ($000) $4,101 Avg Close $49.94 Range $40.04 - $62.95

Q3 2020

Shares 46,954 Value ($000) $2,020 Avg Close $43.43 Range $37.68 - $48.80

Q2 2020

Shares 35,858 Value ($000) $1,485 Avg Close $48.11 Range $35.33 - $61.86

Q3 2019

Shares 14,270 Value ($000) $496 Avg Close $44.70 Range $33.62 - $51.67

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	492,968	$121,538	$210.47	$175.85 - $265.92
Q3 2025	533,964	$94,261	$149.68	$130.50 - $178.20
Q2 2025	505,889	$69,542	$146.88	$122.80 - $182.16
Q1 2025	533,919	$96,270	$168.21	$141.72 - $197.94
Q4 2024	588,599	$92,214	$177.39	$154.16 - $207.84
Q3 2024	600,261	$109,260	$192.81	$164.81 - $219.34
Q2 2024	580,452	$106,593	$167.89	$144.00 - $191.78
Q1 2024	572,915	$101,939	$138.91	$107.50 - $189.97
Q4 2023	550,806	$68,337	$110.89	$93.95 - $129.85
Q3 2023	520,637	$60,396	$122.00	$106.92 - $132.68
Q2 2023	486,597	$57,125	$102.10	$77.09 - $131.80
Q1 2023	462,090	$36,994	$78.56	$69.81 - $89.59
Q4 2022	389,285	$31	$74.22	$61.11 - $81.97
Q3 2022	358,837	$25,012	$72.25	$63.02 - $85.11
Q2 2022	275,923	$18,116	$62.21	$47.67 - $74.53
Q1 2022	262,463	$17,465	$62.42	$50.03 - $73.94
Q4 2021	150,641	$10,538	$58.21	$38.86 - $102.99
Q3 2021	163,864	$8,557	$59.20	$51.04 - $72.55
Q2 2021	213,712	$14,533	$69.80	$59.29 - $83.00
Q1 2021	145,332	$11,192	$72.70	$57.06 - $87.29
Q4 2020	68,344	$4,101	$49.94	$40.04 - $62.95
Q3 2020	46,954	$2,020	$43.43	$37.68 - $48.80
Q2 2020	35,858	$1,485	$48.11	$35.33 - $61.86
Q3 2019	14,270	$496	$44.70	$33.62 - $51.67