KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

CHARLES SCHWAB INVESTMENT MANAGEMENT INC's Holding History (CIK: 0000884546)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 242,774 Value ($000) $59,854 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 242,863 Value ($000) $42,873 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 246,180 Value ($000) $33,840 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 250,514 Value ($000) $45,168 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 243,170 Value ($000) $38,095 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 240,216 Value ($000) $43,727 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 220,439 Value ($000) $40,481 Avg Close $167.89 Range $144.00 - $191.78

Q1 2024

Shares 188,903 Value ($000) $33,612 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 185,038 Value ($000) $22,956 Avg Close $110.89 Range $93.95 - $129.85

Q3 2023

Shares 179,780 Value ($000) $20,854 Avg Close $122.00 Range $106.92 - $132.68

Q2 2023

Shares 162,166 Value ($000) $19,038 Avg Close $102.10 Range $77.09 - $131.80

Q1 2023

Shares 159,889 Value ($000) $12,801 Avg Close $78.56 Range $69.81 - $89.59

Q4 2022

Shares 160,615 Value ($000) $12,724 Avg Close $74.22 Range $61.11 - $81.97

Q3 2022

Shares 156,271 Value ($000) $10,893 Avg Close $72.25 Range $63.02 - $85.11

Q2 2022

Shares 148,752 Value ($000) $9,768 Avg Close $62.21 Range $47.67 - $74.53

Q1 2022

Shares 148,347 Value ($000) $9,872 Avg Close $62.42 Range $50.03 - $73.94

Q4 2021

Shares 139,618 Value ($000) $9,767 Avg Close $58.21 Range $38.86 - $102.99

Q3 2021

Shares 125,384 Value ($000) $6,547 Avg Close $59.20 Range $51.04 - $72.55

Q2 2021

Shares 122,072 Value ($000) $8,301 Avg Close $69.80 Range $59.29 - $83.00

Q1 2021

Shares 114,505 Value ($000) $8,822 Avg Close $72.70 Range $57.06 - $87.29

Q4 2020

Shares 99,179 Value ($000) $5,951 Avg Close $49.94 Range $40.04 - $62.95

Q3 2020

Shares 96,696 Value ($000) $4,163 Avg Close $43.43 Range $37.68 - $48.80

Q2 2020

Shares 76,548 Value ($000) $3,171 Avg Close $48.11 Range $35.33 - $61.86

Q1 2020

Shares 68,903 Value ($000) $2,980 Avg Close $52.30 Range $33.09 - $66.85

Q4 2019

Shares 67,364 Value ($000) $3,731 Avg Close $49.06 Range $31.89 - $66.50

Q3 2019

Shares 66,028 Value ($000) $2,293 Avg Close $44.70 Range $33.62 - $51.67

Q2 2019

Shares 20,839 Value ($000) $840 Avg Close $32.69 Range $22.02 - $46.90

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	242,774	$59,854	$210.47	$175.85 - $265.92
Q3 2025	242,863	$42,873	$149.68	$130.50 - $178.20
Q2 2025	246,180	$33,840	$146.88	$122.80 - $182.16
Q1 2025	250,514	$45,168	$168.21	$141.72 - $197.94
Q4 2024	243,170	$38,095	$177.39	$154.16 - $207.84
Q3 2024	240,216	$43,727	$192.81	$164.81 - $219.34
Q2 2024	220,439	$40,481	$167.89	$144.00 - $191.78
Q1 2024	188,903	$33,612	$138.91	$107.50 - $189.97
Q4 2023	185,038	$22,956	$110.89	$93.95 - $129.85
Q3 2023	179,780	$20,854	$122.00	$106.92 - $132.68
Q2 2023	162,166	$19,038	$102.10	$77.09 - $131.80
Q1 2023	159,889	$12,801	$78.56	$69.81 - $89.59
Q4 2022	160,615	$12,724	$74.22	$61.11 - $81.97
Q3 2022	156,271	$10,893	$72.25	$63.02 - $85.11
Q2 2022	148,752	$9,768	$62.21	$47.67 - $74.53
Q1 2022	148,347	$9,872	$62.42	$50.03 - $73.94
Q4 2021	139,618	$9,767	$58.21	$38.86 - $102.99
Q3 2021	125,384	$6,547	$59.20	$51.04 - $72.55
Q2 2021	122,072	$8,301	$69.80	$59.29 - $83.00
Q1 2021	114,505	$8,822	$72.70	$57.06 - $87.29
Q4 2020	99,179	$5,951	$49.94	$40.04 - $62.95
Q3 2020	96,696	$4,163	$43.43	$37.68 - $48.80
Q2 2020	76,548	$3,171	$48.11	$35.33 - $61.86
Q1 2020	68,903	$2,980	$52.30	$33.09 - $66.85
Q4 2019	67,364	$3,731	$49.06	$31.89 - $66.50
Q3 2019	66,028	$2,293	$44.70	$33.62 - $51.67
Q2 2019	20,839	$840	$32.69	$22.02 - $46.90