KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

BLAIR WILLIAM & CO/IL's Holding History (CIK: 0000902367)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,177 Value ($000) $783 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 4,752 Value ($000) $839 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 4,852 Value ($000) $667 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 9,433 Value ($000) $1,701 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 7,443 Value ($000) $1,166 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 5,568 Value ($000) $1,014 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 5,566 Value ($000) $1,022 Avg Close $167.89 Range $144.00 - $191.78

Q1 2024

Shares 5,602 Value ($000) $997 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 6,152 Value ($000) $763 Avg Close $110.89 Range $93.95 - $129.85

Q3 2023

Shares 6,132 Value ($000) $711 Avg Close $122.00 Range $106.92 - $132.68

Q2 2023

Shares 7,017 Value ($000) $824 Avg Close $102.10 Range $77.09 - $131.80

Q1 2023

Shares 7,057 Value ($000) $565 Avg Close $78.56 Range $69.81 - $89.59

Q4 2022

Shares 6,957 Value ($000) $551 Avg Close $74.22 Range $61.11 - $81.97

Q3 2022

Shares 6,377 Value ($000) $444 Avg Close $72.25 Range $63.02 - $85.11

Q2 2022

Shares 5,092 Value ($000) $334 Avg Close $62.21 Range $47.67 - $74.53

Q4 2021

Shares 8,896 Value ($000) $622 Avg Close $58.21 Range $38.86 - $102.99

Q3 2021

Shares 93,138 Value ($000) $4,863 Avg Close $59.20 Range $51.04 - $72.55

Q2 2021

Shares 58,755 Value ($000) $3,995 Avg Close $69.80 Range $59.29 - $83.00

Q1 2021

Shares 54,166 Value ($000) $4,173 Avg Close $72.70 Range $57.06 - $87.29

Q4 2020

Shares 35,258 Value ($000) $2,115 Avg Close $49.94 Range $40.04 - $62.95

Q3 2020

Shares 36,019 Value ($000) $1,551 Avg Close $43.43 Range $37.68 - $48.80

Q2 2020

Shares 49,899 Value ($000) $2,067 Avg Close $48.11 Range $35.33 - $61.86

Q1 2020

Shares 60,881 Value ($000) $2,632 Avg Close $52.30 Range $33.09 - $66.85

Q4 2019

Shares 63,754 Value ($000) $3,531 Avg Close $49.06 Range $31.89 - $66.50

Q3 2019

Shares 58,491 Value ($000) $2,031 Avg Close $44.70 Range $33.62 - $51.67

Q2 2019

Shares 19,266 Value ($000) $776 Avg Close $32.69 Range $22.02 - $46.90

Q1 2019

Shares 66,206 Value ($000) $2,178 Avg Close $23.57 Range $18.50 - $33.12

Q4 2018

Shares 21,780 Value ($000) $453 Avg Close $20.94 Range $14.30 - $28.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,177	$783	$210.47	$175.85 - $265.92
Q3 2025	4,752	$839	$149.68	$130.50 - $178.20
Q2 2025	4,852	$667	$146.88	$122.80 - $182.16
Q1 2025	9,433	$1,701	$168.21	$141.72 - $197.94
Q4 2024	7,443	$1,166	$177.39	$154.16 - $207.84
Q3 2024	5,568	$1,014	$192.81	$164.81 - $219.34
Q2 2024	5,566	$1,022	$167.89	$144.00 - $191.78
Q1 2024	5,602	$997	$138.91	$107.50 - $189.97
Q4 2023	6,152	$763	$110.89	$93.95 - $129.85
Q3 2023	6,132	$711	$122.00	$106.92 - $132.68
Q2 2023	7,017	$824	$102.10	$77.09 - $131.80
Q1 2023	7,057	$565	$78.56	$69.81 - $89.59
Q4 2022	6,957	$551	$74.22	$61.11 - $81.97
Q3 2022	6,377	$444	$72.25	$63.02 - $85.11
Q2 2022	5,092	$334	$62.21	$47.67 - $74.53
Q4 2021	8,896	$622	$58.21	$38.86 - $102.99
Q3 2021	93,138	$4,863	$59.20	$51.04 - $72.55
Q2 2021	58,755	$3,995	$69.80	$59.29 - $83.00
Q1 2021	54,166	$4,173	$72.70	$57.06 - $87.29
Q4 2020	35,258	$2,115	$49.94	$40.04 - $62.95
Q3 2020	36,019	$1,551	$43.43	$37.68 - $48.80
Q2 2020	49,899	$2,067	$48.11	$35.33 - $61.86
Q1 2020	60,881	$2,632	$52.30	$33.09 - $66.85
Q4 2019	63,754	$3,531	$49.06	$31.89 - $66.50
Q3 2019	58,491	$2,031	$44.70	$33.62 - $51.67
Q2 2019	19,266	$776	$32.69	$22.02 - $46.90
Q1 2019	66,206	$2,178	$23.57	$18.50 - $33.12
Q4 2018	21,780	$453	$20.94	$14.30 - $28.75