KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

FIRST TRUST ADVISORS LP's Holding History (CIK: 0001125816)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 245,276 Value ($000) $60,470 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 248,392 Value ($000) $43,849 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 222,370 Value ($000) $30,567 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 33,125 Value ($000) $5,972 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 23,169 Value ($000) $3,630 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 39,411 Value ($000) $7,174 Avg Close $192.81 Range $164.81 - $219.34

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	245,276	$60,470	$210.47	$175.85 - $265.92
Q3 2025	248,392	$43,849	$149.68	$130.50 - $178.20
Q2 2025	222,370	$30,567	$146.88	$122.80 - $182.16
Q1 2025	33,125	$5,972	$168.21	$141.72 - $197.94
Q4 2024	23,169	$3,630	$177.39	$154.16 - $207.84
Q3 2024	39,411	$7,174	$192.81	$164.81 - $219.34