KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 14,658 Value ($000) $3,614 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 148,713 Value ($000) $26,252 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 12,562 Value ($000) $1,727 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 60,388 Value ($000) $10,888 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 18,956 Value ($000) $2,970 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 47,623 Value ($000) $8,669 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 2,570 Value ($000) $472 Avg Close $167.89 Range $144.00 - $191.78

Q1 2024

Shares 56,635 Value ($000) $10,077 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 8,521 Value ($000) $1,057 Avg Close $110.89 Range $93.95 - $129.85

Q4 2022

Shares 15,123 Value ($000) $1 Avg Close $74.22 Range $61.11 - $81.97

Q2 2022

Shares 15,076 Value ($000) $990 Avg Close $62.21 Range $47.67 - $74.53

Q4 2021

Shares 61,429 Value ($000) $4,297 Avg Close $58.21 Range $38.86 - $102.99

Q3 2021

Shares 24,810 Value ($000) $1,295 Avg Close $59.20 Range $51.04 - $72.55

Q4 2020

Shares 25,544 Value ($000) $1,533 Avg Close $49.94 Range $40.04 - $62.95

Q2 2020

Shares 6,964 Value ($000) $288 Avg Close $48.11 Range $35.33 - $61.86

Q3 2019

Shares 13,954 Value ($000) $484 Avg Close $44.70 Range $33.62 - $51.67

Q2 2019

Shares 119,929 Value ($000) $4,830 Avg Close $32.69 Range $22.02 - $46.90

Q1 2019

Shares 89,155 Value ($000) $2,933 Avg Close $23.57 Range $18.50 - $33.12

Q2 2018

Shares 25,764 Value ($000) $383 Avg Close $11.22 Range $8.91 - $16.00

Q1 2018

Shares 17,198 Value ($000) $174 Avg Close $9.86 Range $8.61 - $12.00

Q4 2017

Shares 25,268 Value ($000) $266 Avg Close $10.02 Range $8.03 - $11.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	14,658	$3,614	$210.47	$175.85 - $265.92
Q3 2025	148,713	$26,252	$149.68	$130.50 - $178.20
Q2 2025	12,562	$1,727	$146.88	$122.80 - $182.16
Q1 2025	60,388	$10,888	$168.21	$141.72 - $197.94
Q4 2024	18,956	$2,970	$177.39	$154.16 - $207.84
Q3 2024	47,623	$8,669	$192.81	$164.81 - $219.34
Q2 2024	2,570	$472	$167.89	$144.00 - $191.78
Q1 2024	56,635	$10,077	$138.91	$107.50 - $189.97
Q4 2023	8,521	$1,057	$110.89	$93.95 - $129.85
Q4 2022	15,123	$1	$74.22	$61.11 - $81.97
Q2 2022	15,076	$990	$62.21	$47.67 - $74.53
Q4 2021	61,429	$4,297	$58.21	$38.86 - $102.99
Q3 2021	24,810	$1,295	$59.20	$51.04 - $72.55
Q4 2020	25,544	$1,533	$49.94	$40.04 - $62.95
Q2 2020	6,964	$288	$48.11	$35.33 - $61.86
Q3 2019	13,954	$484	$44.70	$33.62 - $51.67
Q2 2019	119,929	$4,830	$32.69	$22.02 - $46.90
Q1 2019	89,155	$2,933	$23.57	$18.50 - $33.12
Q2 2018	25,764	$383	$11.22	$8.91 - $16.00
Q1 2018	17,198	$174	$9.86	$8.61 - $12.00
Q4 2017	25,268	$266	$10.02	$8.03 - $11.98