KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

CANADA PENSION PLAN INVESTMENT BOARD's Holding History (CIK: 0001283718)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 600 Value ($000) $148 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 600 Value ($000) $106 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 1,000 Value ($000) $137 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 1,300 Value ($000) $234 Avg Close $168.21 Range $141.72 - $197.94

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	600	$148	$210.47	$175.85 - $265.92
Q3 2025	600	$106	$149.68	$130.50 - $178.20
Q2 2025	1,000	$137	$146.88	$122.80 - $182.16
Q1 2025	1,300	$234	$168.21	$141.72 - $197.94