KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018

Shares 496,071 Value ($000) $5,005 Avg Close $9.86 Range $8.61 - $12.00

Q4 2017

Shares 700,000 Value ($000) $7,364 Avg Close $10.02 Range $8.03 - $11.98

Q3 2017

Shares 700,000 Value ($000) $6,979 Avg Close $10.08 Range $9.42 - $11.31

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2018	496,071	$5,005	$9.86	$8.61 - $12.00
Q4 2017	700,000	$7,364	$10.02	$8.03 - $11.98
Q3 2017	700,000	$6,979	$10.08	$9.42 - $11.31