KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 386,505 Value ($000) $95,289 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 636,988 Value ($000) $112,447 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 34,560 Value ($000) $4,751 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 96 Value ($000) $17 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 11,015 Value ($000) $1,726 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 96 Value ($000) $17 Avg Close $192.81 Range $164.81 - $219.34

Q1 2024

Shares 25,014 Value ($000) $4,451 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 8,199 Value ($000) $1,017 Avg Close $110.89 Range $93.95 - $129.85

Q3 2023

Shares 4,390 Value ($000) $509 Avg Close $122.00 Range $106.92 - $132.68

Q2 2023

Shares 39,288 Value ($000) $4,612 Avg Close $102.10 Range $77.09 - $131.80

Q1 2023

Shares 107,325 Value ($000) $8,592 Avg Close $78.56 Range $69.81 - $89.59

Q4 2022

Shares 52,676 Value ($000) $4,173 Avg Close $74.22 Range $61.11 - $81.97

Q3 2022

Shares 8,738 Value ($000) $609 Avg Close $72.25 Range $63.02 - $85.11

Q1 2022

Shares 8,732 Value ($000) $581 Avg Close $62.42 Range $50.03 - $73.94

Q4 2021

Shares 38,745 Value ($000) $2,710 Avg Close $58.21 Range $38.86 - $102.99

Q3 2021

Shares 31,003 Value ($000) $1,619 Avg Close $59.20 Range $51.04 - $72.55

Q4 2020

Shares 28,708 Value ($000) $1,723 Avg Close $49.94 Range $40.04 - $62.95

Q3 2020

Shares 24,224 Value ($000) $1,043 Avg Close $43.43 Range $37.68 - $48.80

Q2 2020

Shares 21,629 Value ($000) $896 Avg Close $48.11 Range $35.33 - $61.86

Q1 2020

Shares 541,702 Value ($000) $23,423 Avg Close $52.30 Range $33.09 - $66.85

Q4 2019

Shares 536,847 Value ($000) $29,731 Avg Close $49.06 Range $31.89 - $66.50

Q3 2019

Shares 538,226 Value ($000) $18,690 Avg Close $44.70 Range $33.62 - $51.67

Q2 2019

Shares 497,170 Value ($000) $20,021 Avg Close $32.69 Range $22.02 - $46.90

Q1 2019

Shares 322,874 Value ($000) $10,623 Avg Close $23.57 Range $18.50 - $33.12

Q4 2018

Shares 335,029 Value ($000) $6,961 Avg Close $20.94 Range $14.30 - $28.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	386,505	$95,289	$210.47	$175.85 - $265.92
Q3 2025	636,988	$112,447	$149.68	$130.50 - $178.20
Q2 2025	34,560	$4,751	$146.88	$122.80 - $182.16
Q1 2025	96	$17	$168.21	$141.72 - $197.94
Q4 2024	11,015	$1,726	$177.39	$154.16 - $207.84
Q3 2024	96	$17	$192.81	$164.81 - $219.34
Q1 2024	25,014	$4,451	$138.91	$107.50 - $189.97
Q4 2023	8,199	$1,017	$110.89	$93.95 - $129.85
Q3 2023	4,390	$509	$122.00	$106.92 - $132.68
Q2 2023	39,288	$4,612	$102.10	$77.09 - $131.80
Q1 2023	107,325	$8,592	$78.56	$69.81 - $89.59
Q4 2022	52,676	$4,173	$74.22	$61.11 - $81.97
Q3 2022	8,738	$609	$72.25	$63.02 - $85.11
Q1 2022	8,732	$581	$62.42	$50.03 - $73.94
Q4 2021	38,745	$2,710	$58.21	$38.86 - $102.99
Q3 2021	31,003	$1,619	$59.20	$51.04 - $72.55
Q4 2020	28,708	$1,723	$49.94	$40.04 - $62.95
Q3 2020	24,224	$1,043	$43.43	$37.68 - $48.80
Q2 2020	21,629	$896	$48.11	$35.33 - $61.86
Q1 2020	541,702	$23,423	$52.30	$33.09 - $66.85
Q4 2019	536,847	$29,731	$49.06	$31.89 - $66.50
Q3 2019	538,226	$18,690	$44.70	$33.62 - $51.67
Q2 2019	497,170	$20,021	$32.69	$22.02 - $46.90
Q1 2019	322,874	$10,623	$23.57	$18.50 - $33.12
Q4 2018	335,029	$6,961	$20.94	$14.30 - $28.75