KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 1,361 Value ($000) $245 Avg Close $168.21 Range $141.72 - $197.94

Q1 2024

Shares 1,800 Value ($000) $320 Avg Close $138.91 Range $107.50 - $189.97

Q3 2017

Shares 13,786 Value ($000) $137 Avg Close $10.08 Range $9.42 - $11.31

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	1,361	$245	$168.21	$141.72 - $197.94
Q1 2024	1,800	$320	$138.91	$107.50 - $189.97
Q3 2017	13,786	$137	$10.08	$9.42 - $11.31