KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,902 Value ($000) $715 Avg Close $210.47 Range $175.85 - $265.92

Q4 2024

Shares 1,396 Value ($000) $219 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 2,094 Value ($000) $381 Avg Close $192.81 Range $164.81 - $219.34

Q1 2024

Shares 14,127 Value ($000) $2,514 Avg Close $138.91 Range $107.50 - $189.97

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,902	$715	$210.47	$175.85 - $265.92
Q4 2024	1,396	$219	$177.39	$154.16 - $207.84
Q3 2024	2,094	$381	$192.81	$164.81 - $219.34
Q1 2024	14,127	$2,514	$138.91	$107.50 - $189.97