KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

MetLife Investment Management, LLC's Holding History (CIK: 0001529735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 13,844 Value ($000) $3,413 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 14,430 Value ($000) $2,547 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 14,746 Value ($000) $2,027 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 14,524 Value ($000) $2,619 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 14,997 Value ($000) $2,349 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 14,317 Value ($000) $2,606 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 14,317 Value ($000) $2,629 Avg Close $167.89 Range $144.00 - $191.78

Q1 2024

Shares 11,104 Value ($000) $1,976 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 11,371 Value ($000) $1,411 Avg Close $110.89 Range $93.95 - $129.85

Q3 2023

Shares 11,371 Value ($000) $1,319 Avg Close $122.00 Range $106.92 - $132.68

Q2 2023

Shares 11,371 Value ($000) $1,335 Avg Close $102.10 Range $77.09 - $131.80

Q1 2023

Shares 11,181 Value ($000) $895 Avg Close $78.56 Range $69.81 - $89.59

Q4 2022

Shares 11,181 Value ($000) $886 Avg Close $74.22 Range $61.11 - $81.97

Q3 2022

Shares 11,181 Value ($000) $779 Avg Close $72.25 Range $63.02 - $85.11

Q2 2022

Shares 10,266 Value ($000) $674 Avg Close $62.21 Range $47.67 - $74.53

Q1 2022

Shares 10,266 Value ($000) $683 Avg Close $62.42 Range $50.03 - $73.94

Q4 2021

Shares 6,648 Value ($000) $465 Avg Close $58.21 Range $38.86 - $102.99

Q3 2021

Shares 6,648 Value ($000) $347 Avg Close $59.20 Range $51.04 - $72.55

Q2 2021

Shares 6,648 Value ($000) $452 Avg Close $69.80 Range $59.29 - $83.00

Q1 2021

Shares 5,633 Value ($000) $434 Avg Close $72.70 Range $57.06 - $87.29

Q4 2020

Shares 5,633 Value ($000) $338 Avg Close $49.94 Range $40.04 - $62.95

Q3 2020

Shares 5,633 Value ($000) $243 Avg Close $43.43 Range $37.68 - $48.80

Q2 2020

Shares 5,633 Value ($000) $233 Avg Close $48.11 Range $35.33 - $61.86

Q1 2020

Shares 4,509 Value ($000) $195 Avg Close $52.30 Range $33.09 - $66.85

Q4 2019

Shares 4,509 Value ($000) $250 Avg Close $49.06 Range $31.89 - $66.50

Q3 2019

Shares 4,509 Value ($000) $157 Avg Close $44.70 Range $33.62 - $51.67

Q2 2019

Shares 4,509 Value ($000) $182 Avg Close $32.69 Range $22.02 - $46.90

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	13,844	$3,413	$210.47	$175.85 - $265.92
Q3 2025	14,430	$2,547	$149.68	$130.50 - $178.20
Q2 2025	14,746	$2,027	$146.88	$122.80 - $182.16
Q1 2025	14,524	$2,619	$168.21	$141.72 - $197.94
Q4 2024	14,997	$2,349	$177.39	$154.16 - $207.84
Q3 2024	14,317	$2,606	$192.81	$164.81 - $219.34
Q2 2024	14,317	$2,629	$167.89	$144.00 - $191.78
Q1 2024	11,104	$1,976	$138.91	$107.50 - $189.97
Q4 2023	11,371	$1,411	$110.89	$93.95 - $129.85
Q3 2023	11,371	$1,319	$122.00	$106.92 - $132.68
Q2 2023	11,371	$1,335	$102.10	$77.09 - $131.80
Q1 2023	11,181	$895	$78.56	$69.81 - $89.59
Q4 2022	11,181	$886	$74.22	$61.11 - $81.97
Q3 2022	11,181	$779	$72.25	$63.02 - $85.11
Q2 2022	10,266	$674	$62.21	$47.67 - $74.53
Q1 2022	10,266	$683	$62.42	$50.03 - $73.94
Q4 2021	6,648	$465	$58.21	$38.86 - $102.99
Q3 2021	6,648	$347	$59.20	$51.04 - $72.55
Q2 2021	6,648	$452	$69.80	$59.29 - $83.00
Q1 2021	5,633	$434	$72.70	$57.06 - $87.29
Q4 2020	5,633	$338	$49.94	$40.04 - $62.95
Q3 2020	5,633	$243	$43.43	$37.68 - $48.80
Q2 2020	5,633	$233	$48.11	$35.33 - $61.86
Q1 2020	4,509	$195	$52.30	$33.09 - $66.85
Q4 2019	4,509	$250	$49.06	$31.89 - $66.50
Q3 2019	4,509	$157	$44.70	$33.62 - $51.67
Q2 2019	4,509	$182	$32.69	$22.02 - $46.90