KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC's Holding History (CIK: 0001644956)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 376,340 Value ($000) $92,783 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 149,302 Value ($000) $26,356 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 91,099 Value ($000) $12,522 Avg Close $146.88 Range $122.80 - $182.16

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	376,340	$92,783	$210.47	$175.85 - $265.92
Q3 2025	149,302	$26,356	$149.68	$130.50 - $178.20
Q2 2025	91,099	$12,522	$146.88	$122.80 - $182.16