KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

Vanguard Personalized Indexing Management, LLC's Holding History (CIK: 0001767306)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,127 Value ($000) $524 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 2,011 Value ($000) $355 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 1,695 Value ($000) $233 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 1,946 Value ($000) $351 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 1,400 Value ($000) $219 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 1,538 Value ($000) $280 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 1,374 Value ($000) $252 Avg Close $167.89 Range $144.00 - $191.78

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,127	$524	$210.47	$175.85 - $265.92
Q3 2025	2,011	$355	$149.68	$130.50 - $178.20
Q2 2025	1,695	$233	$146.88	$122.80 - $182.16
Q1 2025	1,946	$351	$168.21	$141.72 - $197.94
Q4 2024	1,400	$219	$177.39	$154.16 - $207.84
Q3 2024	1,538	$280	$192.81	$164.81 - $219.34
Q2 2024	1,374	$252	$167.89	$144.00 - $191.78