KRYSTAL BIOTECH INC

Ticker: KRYS CUSIP: 501147102 Class: Common Stock

Pictet Asset Management Holding SA's Holding History (CIK: 0001993888)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 156,568 Value ($000) $38,600 Avg Close $210.47 Range $175.85 - $265.92

Q3 2025

Shares 196,904 Value ($000) $34,759 Avg Close $149.68 Range $130.50 - $178.20

Q2 2025

Shares 130,537 Value ($000) $17,944 Avg Close $146.88 Range $122.80 - $182.16

Q1 2025

Shares 65,262 Value ($000) $11,767 Avg Close $168.21 Range $141.72 - $197.94

Q4 2024

Shares 112,089 Value ($000) $17,560 Avg Close $177.39 Range $154.16 - $207.84

Q3 2024

Shares 115,350 Value ($000) $20,997 Avg Close $192.81 Range $164.81 - $219.34

Q2 2024

Shares 137,433 Value ($000) $25,238 Avg Close $167.89 Range $144.00 - $191.78

Q1 2024

Shares 142,960 Value ($000) $25,437 Avg Close $138.91 Range $107.50 - $189.97

Q4 2023

Shares 192,875 Value ($000) $23,928 Avg Close $110.89 Range $93.95 - $129.85

Q3 2023

Shares 373,812 Value ($000) $43,362 Avg Close $122.00 Range $106.92 - $132.68

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	156,568	$38,600	$210.47	$175.85 - $265.92
Q3 2025	196,904	$34,759	$149.68	$130.50 - $178.20
Q2 2025	130,537	$17,944	$146.88	$122.80 - $182.16
Q1 2025	65,262	$11,767	$168.21	$141.72 - $197.94
Q4 2024	112,089	$17,560	$177.39	$154.16 - $207.84
Q3 2024	115,350	$20,997	$192.81	$164.81 - $219.34
Q2 2024	137,433	$25,238	$167.89	$144.00 - $191.78
Q1 2024	142,960	$25,437	$138.91	$107.50 - $189.97
Q4 2023	192,875	$23,928	$110.89	$93.95 - $129.85
Q3 2023	373,812	$43,362	$122.00	$106.92 - $132.68