KYTHERA BIOPHARMACEUTICALS I

CUSIP: 501570105 Class: COM

ROYAL BANK OF CANADA's Holding History (CIK: 0001000275)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 191,753 Value ($000) $14,377 Avg Close — Range —
Q2 2015
Shares 4,511 Value ($000) $340 Avg Close — Range —
Q1 2015
Shares 38,165 Value ($000) $1,914 Avg Close — Range —
Q4 2014
Shares 900 Value ($000) $31 Avg Close — Range —
Q3 2014
Shares 300 Value ($000) $10 Avg Close — Range —
Q2 2014
Shares 17,300 Value ($000) $664 Avg Close — Range —
Q4 2013
Shares 27,700 Value ($000) $1,035 Avg Close — Range —
Q3 2013
Shares 48,161 Value ($000) $2,201 Avg Close — Range —
Q2 2013
Shares 74,800 Value ($000) $2,023 Avg Close — Range —