KYTHERA BIOPHARMACEUTICALS I

CUSIP: 501570105 Class: COM

Redmile Group, LLC's Holding History (CIK: 0001425738)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 482,556 Value ($000) $36,341 Avg Close — Range —
Q1 2015
Shares 225,062 Value ($000) $11,287 Avg Close — Range —
Q3 2014
Shares 281,479 Value ($000) $9,221 Avg Close — Range —
Q2 2014
Shares 560,356 Value ($000) $21,501 Avg Close — Range —
Q1 2014
Shares 443,326 Value ($000) $17,627 Avg Close — Range —
Q4 2013
Shares 557,761 Value ($000) $20,777 Avg Close — Range —
Q3 2013
Shares 228,218 Value ($000) $10,430 Avg Close — Range —
Q2 2013
Shares 110,118 Value ($000) $2,979 Avg Close — Range —
Q1 2013
Shares 108,118 Value ($000) $2,634 Avg Close — Range —