LEXICON PHARMACEUTICALS INC

CUSIP: 528872104 Class: CMN

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 1,636,131 Value ($000) $1,545 Avg Close — Range —
Q4 2014
Shares 695,910 Value ($000) $633 Avg Close — Range —
Q4 2013
Shares 246,345 Value ($000) $443 Avg Close — Range —